Our study, published recently in the IJE, looks at the relationship between experience of violence, in the form of physical assault in the previous 12 months, and premature mortality in a sample of working-age Russian men living in Izhevsk in the Southern Urals.
In contrast, we found that population-based research on the physical health effects of exposure to violence was limited, and we decided to focus on possible associations between assault and mortality in our study.
Metabolic phenotyping, nowadays most often termed metabolomics, is becoming increasingly applied in epidemiology. Recent technological developments, driven by mass spectrometry and nuclear magnetic resonance spectroscopy, have recently resulted in increasing numbers of quantitative molecular applications at an epidemiological scale. The results suggest that these kinds of new technologies are inevitably becoming common in research projects aiming for molecular understanding of metabolic health and diseases. It is also evident from the epidemiological applications that absolute quantification of identified molecular entities is the very key for biomedical applications, not to mention potential clinical translation of metabolomics methodologies and findings. Continue reading “Metabolic Phenotyping in Epidemiology”→
When Michael Bloomberg was elected Mayor of New York City (NYC), he set forth an ambitious agenda to efficiently sync municipal agencies. Improving New Yorkers’ health was part of his motivation. For example, expanding parks and bike lanes would not only improve people’s quality of life and expand transportation options, their presence would also encourage healthy behaviours. So, why not create cross-agency agendas that allow parks with bike lanes to be created on city streets? Innovative thinkers were hired and were given an unusual amount of political capital and logistical support to implement their plans.
World AIDS Day is held on 1 December every year and provides an opportunity for people across the globe to show solidarity with the millions of people living with HIV. This year’s campaign theme is ‘HIV Stigma: Not Retro, Just Wrong’ #HIVNotRetro and you can find out more about how to get involved at https://www.worldaidsday.org/.
Rheumatic Heart Disease (RHD) is caused by a bacterial (streptococcal) throat infection acquired in childhood. Although this type of infection is common and widespread, a small proportion of children so affected go on to develop an inflammatory condition that leads to scarring and narrowing of the heart valves and, in time, heart failure. Early on in the course of the disease the joints may be affected – hence the term “rheumatic”.
Still an important disease At one time Rheumatic Heart Disease was common throughout the UK, Europe and the US; it was the most important cause of heart disease among young adults in Victorian Britain and probably caused the death of Mozart. Although rare now in most developed countries, it remains an important public health problem in many low and middle income countries. The disease is widespread in the Middle East and Asia, and the the poor indigenous populations of some wealthy countries, for example among Australian Aboriginees and New Zealand Maoris. It is particularly prevalent in sub-Saharan Africa, where it is one of the commonest causes of heart disease, typically affecting children or young adults. There it carries a grim prognosis because of the lack of specialised treatment. Continue reading “Smoke exposure in early life and Rheumatic Heart Disease”→
The IJE conference took place in Bristol on 7 October 2016, a one-day, one-off event.
Rodolfo Saracci, as ever bow-tied and in good spirits, did the honours throughout the day. It was under his IEA presidency that Shah Ebrahim and George Davey Smith were hired as IJE editors, and Rodolfo praised their editorial work by likening it to conducting research (“exciting, adventurous, challenging”), and acknowledging that brave decisions have exposed them to the future judgement of historians.
Today marks the end of an era. The International Journal of Epidemiology used to be a typical hotchpotch of isolated papers on worthy subjects. Occasionally, some were interesting, or related to your field. Under Shah Ebrahim and George Davey Smith it became like nothing else: an epidemiology journal you’d happily subscribe to with your own money, and read in the bath. Continue reading “You should totally watch this entire day of the IJE conference”→
Metabolic phenotyping, nowadays most often termed metabolomics, is becoming increasingly applied in molecular epidemiology. Recent technological developments resulting in increased numbers of quantitative molecular applications of metabolomics triggered the idea for a themed issue of the IJE on Metabolic Phenotyping in Epidemiology edited by George Davey Smith and myself. Continue reading “Metabolic Phenotyping in Epidemiology”→
Cecilie Svanes, Jennifer Koplin, Francisco Gomez Real, and Svein Magne Skulstad
A new study shows that asthma is three times more common in those who had a father who smoked in adolescence, and twice as common in those whose father worked with welding before conception. Can these numbers be reduced by including adolescent boys in public health prevention programmes?
It is well known that a mother’s environment plays a key role in child health. The hypothesis that health and disease originate early in life has dramatically increased our understanding of this issue. However, recent research suggests that this may also be true for fathers; i.e. father’s lifestyle and age appear to be reflected in molecules that control gene function. There is growing evidence from animal studies for “epigenetic” inheritance, a mechanism whereby the father’s environment before conception could impact on the health of future generations. Continue reading “Does fathers’ smoking give their future offspring asthma?”→