Asthma and type 1 diabetes in childhood: new insights into their association

Johanna Metsälä, Jaakko Nevalainen and Suvi M Virtanen


Traditionally, asthma and type 1 diabetes have been considered distinct immune-mediated diseases in which the underlying immune responses counteract each other, resulting in an inverse association between the diseases. In our study, recently published in the IJE, we explored the association between asthma and type 1 diabetes in childhood in a novel way, and observed that the direction of the association is dependent on the order of appearance of the diseases.

Continue reading “Asthma and type 1 diabetes in childhood: new insights into their association”

Does fathers’ smoking give their future offspring asthma?

Cecilie Svanes, Jennifer Koplin, Francisco Gomez Real, and Svein Magne SkulstadSlide1

A new study shows that asthma is three times more common in those who had a father who smoked in adolescence, and twice as common in those whose father worked with welding before conception. Can these numbers be reduced by including adolescent boys in public health prevention programmes?

It is well known that a mother’s environment plays a key role in child health. The hypothesis that health and disease originate early in life has dramatically increased our understanding of this issue. However, recent research suggests that this may also be true for fathers; i.e. father’s lifestyle and age appear to be reflected in molecules that control gene function. There is growing evidence from animal studies for “epigenetic” inheritance, a mechanism whereby the father’s environment before conception could impact on the health of future generations. Continue reading “Does fathers’ smoking give their future offspring asthma?”